SRF full form in medical is Serum Response Factor. This is a certain kind of protein that plays an important role in cell differentiation and gene regulation. It operates the expression of various genes, including in proliferation, cell development, and differentiation, and attaches to DNA in a certain order. In the growth of smooth muscle cells, skeletal and cardiac, SRF is essential. Sudden alterations in the SRF have been associated with a number of diseases, such as cancer, cardiovascular disease, and neurological disorders.
This protein encompasses various operative areas, such as a Dimerization domain, a DNA-binding domain, and an activation domain. The dimerization field enables SRF to produce heterodimers and other transcription elements. On the other side, the DNA-biding field authorizes and joints to the SRE in the area of target genes.
The role of SRF is to regulate the appearance of genes, including proliferation, cell growth, survival, and differentiation. Smooth Muscle Actin, Myosin Light Chain, and Tropomyosin are the major target genes of SRF. They play an important role in cell motility and muscle contraction. It also operates the function of various other genes developing in the process of the immune system, nervous system, and cardiovascular.