FPP Full Form in Medical is Foramina parietalia permagna. A primary ossification imperfection known as foramina parietalia permagna can be found at the level of parietal eminence. It is possible for it to manifest itself in early children as a chronically expanded posterior fontanelle, with the following ossification of a middle bridge during infancy resulting in the formation of two foramina.
Although it may be associated with headaches, nausea, vomiting, intellectual disability, and sometimes even other malformations such as cerebrovascular abnormalities, multiple exostosis, syndactyly, craniofacial dysostosis, eye or ear abnormalities, microcephaly, cortical dysplasia, or craniosynostosis.
FPP is typically asymptomatic in the majority of cases. 85 percent of cases are caused by genetic variations that have an autosomal dominant inheritance pattern together with a significant but inadequate penetrance.
The diagnosis of FPP is made based on the patient’s medical history and their physical examination, with the addition of imaging tests being an option. The chest radiograph will show symmetric lucencies in parasagittal zone of the parietal bones, the computed tomography with 3D reconstruction will be able to demarcate the bony defect, and the magnetic resonance (MRI) will be able to detect other affiliated intracranial abnormalities.